Liver volume calculator (CT/MRI)

Notes

• This calculator uses the following formula:
  • Volume = CC x LL x AP x 0.31
    • ^{Muggli D, Müller MA, Karlo C, Fornaro J, Marincek B, Frauenfelder T. A simple method to approximate liver size on cross-sectional images using living liver models. Clin Radiol. 2009 Jul;64(7):682-9. doi: 10.1016/j.crad.2009.02.013. Epub 2009 May 7. PMID: 19520212.}
• Note that the standard liver volume is variable across populations and therefore it is not possible to define clear cut-off values without knowledge of the patient demographics. E.g. for a western adult population the following formula was proposed to estimate the expected(!) liver volume dependent on body habitus:
  • Total liver volume = 191.8 + (18.51 x weight in kgs)
    • ^{Vauthey JN, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, Lerut J, Materne R, Wang X, Encarnacion A, Herron D, Mathey C, Ferrari G, Charnsangavej C, Do KA, Denys A. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl. 2002 Mar;8(3):233-40. doi: 10.1053/jlts.2002.31654. PMID: 11910568.}

• It is also worth mentioning that the liver volume follows a circadian rhythm (-7.5 to + 3.2%) due to hydration, physical activity, and nutrition. The minimum volume is usually found at midday.
  • ^{Leung NW, Farrant P, Peters TJ. Liver volume measurement by ultrasonography in normal subjects and alcoholic patients. J Hepatol. 1986;2(2):157-64. doi: 10.1016/s0168-8278(86)80074-5. PMID: 3514743.}

Last updated: 2021-11-18